KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes

OBJECTIVE: Increasing plasma levels and activity of dipeptidyl peptidase-4 (DPP4 or CD26) are associated with rapid progression of metabolic syndrome to overt type 2 diabetes mellitus (T2DM). While DPP4 inhibitors are increasingly used as anti-hyperglycemic agents, the reason for the increase in pla...

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Detalles Bibliográficos
Autores principales: Nargis, Titli, Kumar, Krishna, Ghosh, Amrit Raj, Sharma, Amit, Rudra, Dipayan, Sen, Debrup, Chakrabarti, Saikat, Mukhopadhyay, Satinath, Ganguly, Dipyaman, Chakrabarti, Partha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681279/
https://www.ncbi.nlm.nih.gov/pubmed/29107298
http://dx.doi.org/10.1016/j.molmet.2017.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681279/
https://www.ncbi.nlm.nih.gov/pubmed/29107298
http://dx.doi.org/10.1016/j.molmet.2017.09.004

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