Genetic anticipation in Swedish Lynch syndrome families

Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have...

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Detalles Bibliográficos
Autores principales: von Salomé, Jenny, Boonstra, Philip S., Karimi, Masoud, Silander, Gustav, Stenmark-Askmalm, Marie, Gebre-Medhin, Samuel, Aravidis, Christos, Nilbert, Mef, Lindblom, Annika, Lagerstedt-Robinson, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681299/
https://www.ncbi.nlm.nih.gov/pubmed/29088233
http://dx.doi.org/10.1371/journal.pgen.1007012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681299/
https://www.ncbi.nlm.nih.gov/pubmed/29088233
http://dx.doi.org/10.1371/journal.pgen.1007012

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