Synthesis and anticancer activity of new quinazoline derivatives

In this study, a new series of quinazoline derivatives (3–26) was synthesized and characterized via physicochemical and spectral means. Treatment of 2-amino-5-methylbenzoic acid with butyl isothiocyanate resulted in the new 2-thioxoquinazolin-4-one (3). Alkylation and hydrazinolysis of the inherent...

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Detalles Bibliográficos
Autores principales: Abuelizz, Hatem A., Marzouk, Mohamed, Ghabbour, Hazem, Al-Salahi, Rashad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681317/
https://www.ncbi.nlm.nih.gov/pubmed/29158714
http://dx.doi.org/10.1016/j.jsps.2017.04.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681317/
https://www.ncbi.nlm.nih.gov/pubmed/29158714
http://dx.doi.org/10.1016/j.jsps.2017.04.022

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