Cargando…
Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells
Advanced head and neck squamous cell carcinoma (HNSCC) remains a therapeutic challenge due to the development of therapy resistance. Several studies have implicated the development of cancer stem cells as a possible mechanism for therapy resistance in HNSCC. Heat shock protein 90’s (Hsp90’s) molecul...
Autores principales: | Subramanian, C., Kovatch, K.J., Sim, M.W., Wang, G., Prince, M.E., Carey, T.E., Davis, R., Blagg, B.S.J., Cohen, M.S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681325/ https://www.ncbi.nlm.nih.gov/pubmed/29121598 http://dx.doi.org/10.1016/j.neo.2017.09.003 |
Ejemplares similares
-
Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells
por: Shi, Lingfang, et al.
Publicado: (2007) -
C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties
por: Inagawa, Takabumi, et al.
Publicado: (2020) -
Ku circles the telomere?
por: Sell, Christian
Publicado: (2011) -
Ku and the Stability of the Genome
por: Friedl, Anna A.
Publicado: (2002) -
EAF2 regulates DNA repair through Ku70/Ku80 in the prostate
por: Ai, J, et al.
Publicado: (2017)