Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

Tauopathies are a group of neurodegenerative disorders where TAU protein is presented as aggregates or is abnormally phosphorylated, leading to alterations of axonal transport, neuronal death and neuroinflammation. Currently, there is no treatment to slow progression of these diseases. Here, we have...

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Detalles Bibliográficos
Autores principales: Cuadrado, Antonio, Kügler, Sebastian, Lastres-Becker, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681345/
https://www.ncbi.nlm.nih.gov/pubmed/29121589
http://dx.doi.org/10.1016/j.redox.2017.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681345/
https://www.ncbi.nlm.nih.gov/pubmed/29121589
http://dx.doi.org/10.1016/j.redox.2017.10.010

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