Cargando…
Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
Tauopathies are a group of neurodegenerative disorders where TAU protein is presented as aggregates or is abnormally phosphorylated, leading to alterations of axonal transport, neuronal death and neuroinflammation. Currently, there is no treatment to slow progression of these diseases. Here, we have...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681345/ https://www.ncbi.nlm.nih.gov/pubmed/29121589 http://dx.doi.org/10.1016/j.redox.2017.10.010 |