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Human Prolactin Point Mutations and Their Projected Effect on Vasoinhibin Generation and Vasoinhibin-Related Diseases

BACKGROUND: A dysregulation of the generation of vasoinhibin hormones by proteolytic cleavage of prolactin (PRL) has been brought into context with diabetic retinopathy, retinopathy of prematurity, preeclampsia, pregnancy-induced hypertension, and peripartum cardiomyopathy. Factors governing vasoinh...

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Detalles Bibliográficos
Autores principales: Triebel, Jakob, Friedrich, Christin J., Leuchs, Andreas, Martínez de la Escalera, Gonzalo, Clapp, Carmen, Bertsch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681482/
https://www.ncbi.nlm.nih.gov/pubmed/29163363
http://dx.doi.org/10.3389/fendo.2017.00294