Probing the mechanical stability of bridged DNA-H-NS protein complexes by single-molecule AFM pulling

Atomic force microscopy (AFM) has proven to be a powerful tool for the study of DNA-protein interactions due to its ability to image single molecules at the nanoscale. However, the use of AFM in force spectroscopy to study DNA-protein interactions has been limited. Here we developed a high throughpu...

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Detalles Bibliográficos
Autores principales: Liang, Yan, van der Valk, Ramon A., Dame, Remus T., Roos, Wouter H., Wuite, Gijs J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681504/
https://www.ncbi.nlm.nih.gov/pubmed/29127381
http://dx.doi.org/10.1038/s41598-017-15477-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681504/
https://www.ncbi.nlm.nih.gov/pubmed/29127381
http://dx.doi.org/10.1038/s41598-017-15477-4

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