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Probing the mechanical stability of bridged DNA-H-NS protein complexes by single-molecule AFM pulling
Atomic force microscopy (AFM) has proven to be a powerful tool for the study of DNA-protein interactions due to its ability to image single molecules at the nanoscale. However, the use of AFM in force spectroscopy to study DNA-protein interactions has been limited. Here we developed a high throughpu...
Autores principales: | Liang, Yan, van der Valk, Ramon A., Dame, Remus T., Roos, Wouter H., Wuite, Gijs J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681504/ https://www.ncbi.nlm.nih.gov/pubmed/29127381 http://dx.doi.org/10.1038/s41598-017-15477-4 |
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