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Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

Cerebrospinal fluid (CSF) has been commonly accepted to drain through arachnoid projections from the subarachnoid space to the dural venous sinuses. However, a lymphatic component to CSF outflow has long been known. Here, we utilize lymphatic-reporter mice and high-resolution stereomicroscopy to cha...

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Detalles Bibliográficos
Autores principales: Ma, Qiaoli, Ineichen, Benjamin V., Detmar, Michael, Proulx, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681558/
https://www.ncbi.nlm.nih.gov/pubmed/29127332
http://dx.doi.org/10.1038/s41467-017-01484-6