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Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

Humoral immunity requires B cells to respond to multiple stimuli, including antigen, membrane and soluble ligands, and microbial products. Ets family transcription factors regulate many aspects of haematopoiesis, although their functions in humoral immunity are difficult to decipher as a result of r...

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Detalles Bibliográficos
Autores principales: Willis, Simon N., Tellier, Julie, Liao, Yang, Trezise, Stephanie, Light, Amanda, O’Donnell, Kristy, Garrett-Sinha, Lee Ann, Shi, Wei, Tarlinton, David M., Nutt, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681560/
https://www.ncbi.nlm.nih.gov/pubmed/29127283
http://dx.doi.org/10.1038/s41467-017-01605-1