Frequency of Human CD45+ Target Cells is a Key Determinant of Intravaginal HIV-1 Infection in Humanized Mice

Approximately 40% of HIV-1 infections occur in the female genital tract (FGT), primarily through heterosexual transmission. FGT factors determining outcome of HIV-1 exposure are incompletely understood, limiting prevention strategies. Here, humanized NOD-Rag1(−/−) γc(−/−) mice differentially reconst...

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Detalles Bibliográficos
Autores principales: Nguyen, Philip V., Wessels, Jocelyn M., Mueller, Kristen, Vahedi, Fatemeh, Anipindi, Varun, Verschoor, Chris P., Chew, Marianne, Deshiere, Alexandre, Karniychuk, Uladzimir, Mazzulli, Tony, Tremblay, Michel J., Ashkar, Ali A., Kaushic, Charu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681573/
https://www.ncbi.nlm.nih.gov/pubmed/29127409
http://dx.doi.org/10.1038/s41598-017-15630-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681573/
https://www.ncbi.nlm.nih.gov/pubmed/29127409
http://dx.doi.org/10.1038/s41598-017-15630-z

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