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A Mouse Model of Autoimmune Cholangitis via Syngeneic Bile Duct Protein Immunization
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the destruction of interlobular biliary ductules, which progressively leads to cholestasis, hepatic fibrosis, cirrhosis, and eventually liver failure. Several mouse models have been used to clarify the pathogenesis of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681628/ https://www.ncbi.nlm.nih.gov/pubmed/29127360 http://dx.doi.org/10.1038/s41598-017-15661-6 |