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A Mouse Model of Autoimmune Cholangitis via Syngeneic Bile Duct Protein Immunization

Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the destruction of interlobular biliary ductules, which progressively leads to cholestasis, hepatic fibrosis, cirrhosis, and eventually liver failure. Several mouse models have been used to clarify the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Ma, Wen-Tao, Liu, Qing-Zhi, Yang, Jing-Bo, Yang, Yan-Qing, Zhao, Zhi-Bin, Ma, Hong-Di, Gershwin, M. Eric, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681628/
https://www.ncbi.nlm.nih.gov/pubmed/29127360
http://dx.doi.org/10.1038/s41598-017-15661-6