Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer

Colon cancers are composed of phenotypically heterogeneous tumor cell subpopulations with variable expression of putative stem cell and differentiation antigens. While in normal colonic mucosa, clonal repopulation occurs along differentiation gradients from crypt base toward crypt apex, the clonal a...

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Detalles Bibliográficos
Autores principales: Lamprecht, Sebastian, Schmidt, Eva Marina, Blaj, Cristina, Hermeking, Heiko, Jung, Andreas, Kirchner, Thomas, Horst, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681634/
https://www.ncbi.nlm.nih.gov/pubmed/29127276
http://dx.doi.org/10.1038/s41467-017-00976-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681634/
https://www.ncbi.nlm.nih.gov/pubmed/29127276
http://dx.doi.org/10.1038/s41467-017-00976-9

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