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The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline c...

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Detalles Bibliográficos
Autores principales: Ernst, Christina, Odom, Duncan T., Kutter, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681665/
https://www.ncbi.nlm.nih.gov/pubmed/29127279
http://dx.doi.org/10.1038/s41467-017-01049-7