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The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681665/ https://www.ncbi.nlm.nih.gov/pubmed/29127279 http://dx.doi.org/10.1038/s41467-017-01049-7 |