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Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes

Allogeneic hematopoietic stem cell transplantation (HSCT) is a critically important therapy for hematological malignancies, inborn errors of metabolism, and immunodeficiency disorders, yet complications such as graft-vs.-host disease (GvHD) limit survival. Development of anti-GvHD therapies that do...

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Detalles Bibliográficos
Autores principales: Burwitz, Benjamin J., Wu, Helen L., Abdulhaqq, Shaheed, Shriver-Munsch, Christine, Swanson, Tonya, Legasse, Alfred W., Hammond, Katherine B., Junell, Stephanie L., Reed, Jason S., Bimber, Benjamin N., Greene, Justin M., Webb, Gabriela M., Northrup, Mina, Laub, Wolfram, Kievit, Paul, MacAllister, Rhonda, Axthelm, Michael K., Ducore, Rebecca, Lewis, Anne, Colgin, Lois M. A., Hobbs, Theodore, Martin, Lauren D., Ferguson, Betsy, Thomas Jr., Charles R., Panoskaltsis-Mortari, Angela, Meyers, Gabrielle, Stanton, Jeffrey J., Maziarz, Richard T., Sacha, Jonah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681693/
https://www.ncbi.nlm.nih.gov/pubmed/29127275
http://dx.doi.org/10.1038/s41467-017-01631-z