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Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se)

BACKGROUND: Severe sepsis and septic shock remain a major challenge, even in modern intensive care. In Germany, about 68,000 patients die annually because of septic diseases, characterized by a complex systemic inflammatory response. Causal treatment of the underlying infection is essential for succ...

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Detalles Bibliográficos
Autores principales: Zimmermann, Johannes B., Pinder, Nadine, Bruckner, Thomas, Lehmann, Monika, Motsch, Johann, Brenner, Thorsten, Hoppe-Tichy, Torsten, Swoboda, Stefanie, Weigand, Markus A., Hofer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681758/
https://www.ncbi.nlm.nih.gov/pubmed/29126416
http://dx.doi.org/10.1186/s13063-017-2231-x