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Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

BACKGROUND: Administration of bone marrow mononuclear cells (BMMCs) modulates lung inflammation and fibrosis in experimental silicosis. However, no studies have evaluated whether silicosis affects the efficacy of autologous BMMCs treatment. We hypothesized that BMMCs obtained from healthy or silicot...

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Detalles Bibliográficos
Autores principales: de Oliveira, Helena D’Anunciação, de Melo, Elga Bernardo Bandeira, Silva, Johnatas Dutra, Kitoko, Jamil Zola, Gutfilen, Bianca, Barboza, Thiago, de Souza, Sergio Augusto Lopes, Takiya, Christina Maeda, Rocco, Patricia Rieken Macedo, Lopes-Pacheco, Miquéias, Morales, Marcelo Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681761/
https://www.ncbi.nlm.nih.gov/pubmed/29126438
http://dx.doi.org/10.1186/s13287-017-0699-7