RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism

BACKGROUND: The association of eosinophils with inflammation and tissue remodeling is at least partially due to their release of toxic granule proteins and other mediators, including cytokines. Tissue remodeling and consequent functional defects are affected by activity of connective tissue fibrobla...

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Detalles Bibliográficos
Autores principales: Esnault, Stephane, Bernau, Ksenija, Torr, Elizabeth E., Bochkov, Yury A., Jarjour, Nizar N., Sandbo, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681771/
https://www.ncbi.nlm.nih.gov/pubmed/29126429
http://dx.doi.org/10.1186/s12931-017-0669-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681771/
https://www.ncbi.nlm.nih.gov/pubmed/29126429
http://dx.doi.org/10.1186/s12931-017-0669-8

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