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Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation

BACKGROUND: Lung cancer is the leading cause of cancer death worldwide. However, the molecular mechanisms underlying lung cancer development have not been fully understood. The functions of histone deacetylases (HDACs), a class of total eighteen proteins (HDAC1–11 and SIRT1–7 in mammals) that deacet...

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Detalles Bibliográficos
Autores principales: Lei, Yubin, Liu, Lingling, Zhang, Shujing, Guo, Shicheng, Li, Xiaoqing, Wang, Jiucun, Su, Bo, Fang, Yuchao, Chen, Xiaofeng, Ke, Hengning, Tao, Wufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681774/
https://www.ncbi.nlm.nih.gov/pubmed/29126425
http://dx.doi.org/10.1186/s12943-017-0736-2