Cargando…

Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation

BACKGROUND: Lung cancer is the leading cause of cancer death worldwide. However, the molecular mechanisms underlying lung cancer development have not been fully understood. The functions of histone deacetylases (HDACs), a class of total eighteen proteins (HDAC1–11 and SIRT1–7 in mammals) that deacet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Yubin, Liu, Lingling, Zhang, Shujing, Guo, Shicheng, Li, Xiaoqing, Wang, Jiucun, Su, Bo, Fang, Yuchao, Chen, Xiaofeng, Ke, Hengning, Tao, Wufan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681774/ https://www.ncbi.nlm.nih.gov/pubmed/29126425 http://dx.doi.org/10.1186/s12943-017-0736-2

Ejemplares similares

NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2017)

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis
por: Winter, Mircea, et al.
Publicado: (2013)

Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis
por: Wang, Tao, et al.
Publicado: (2022)

Combination antiretroviral therapy is associated with reduction in liver fibrosis scores in patients with HIV and HBV co-infection
por: Yang, Rongrong, et al.
Publicado: (2021)

STAT1 and STAT3 in tumorigenesis: A matter of balance
por: Avalle, Lidia, et al.
Publicado: (2012)

miR-944 inhibits lung adenocarcinoma tumorigenesis by targeting STAT1 interaction
por: An, Jing Chun, et al.
Publicado: (2019)

CREPT Disarms the Inhibitory Activity of HDAC1 on Oncogene Expression to Promote Tumorigenesis
por: Cao, Yajun, et al.
Publicado: (2022)

JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice
por: Gonneaud, Alexis, et al.
Publicado: (2021)

MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway
por: Zhao, Qun, et al.
Publicado: (2021)

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape
por: Conte, Mariarosaria, et al.
Publicado: (2014)

Two outbreaks of SARS-CoV-2 in department of surgery in a Wuhan hospital
por: Gao, Shicheng, et al.
Publicado: (2020)

Downregulation of Homeobox B7 Inhibits the Tumorigenesis and Progression of Osteosarcoma
por: Yang, Lei, et al.
Publicado: (2017)

Chidamide induces apoptosis in DLBCL cells by suppressing the HDACs/STAT3/Bcl-2 pathway
por: Zhang, Hongwei, et al.
Publicado: (2021)

Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis
por: Li, Song, et al.
Publicado: (2011)

Expression of Histone Deacetylases HDAC1, HDAC2, HDAC3, and HDAC6 in Invasive Ductal Carcinomas of the Breast
por: Seo, Jinwon, et al.
Publicado: (2014)

Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3-NF-κB signaling
por: Ai, Xiao-Yu, et al.
Publicado: (2017)

Involvement of STAT3 in immune evasion during lung tumorigenesis
por: Kida, Hiroshi, et al.
Publicado: (2013)

Hipk is required for JAK/STAT activity during development and tumorigenesis
por: Tettweiler, Gritta, et al.
Publicado: (2019)

miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis
por: Hsieh, Tsung-Hua, et al.
Publicado: (2014)

Expressional Difference of RHEB, HDAC1, and WEE1 Proteins in the Stromal Tumors of the Breast and Their Significance in Tumorigenesis
por: Eom, Minseob, et al.
Publicado: (2012)

MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis
por: Yang, Chuan He, et al.
Publicado: (2016)

HDAC8 and STAT3 repress BMF gene activity in colon cancer cells
por: Kang, Y, et al.
Publicado: (2014)

Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability
por: Ma, Zhi-Qiang, et al.
Publicado: (2022)

Organogenesis and tumorigenesis: Insight from the JAK/STAT pathway in the Drosophila eye
por: Wang, Ying-Hsuan, et al.
Publicado: (2010)

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis
por: Grabner, Beatrice, et al.
Publicado: (2015)

IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer
por: Sakahara, Mizuho, et al.
Publicado: (2019)

UBE2T/STAT3 Signaling Promotes the Proliferation and Tumorigenesis in Retinoblastoma
por: Xu, Nuo, et al.
Publicado: (2022)

STAT2 Controls Colorectal Tumorigenesis and Resistance to Anti-Cancer Drugs
por: Chiriac, Mircea T., et al.
Publicado: (2023)

SLCO1B3 promotes colorectal cancer tumorigenesis and metastasis through STAT3
por: Zhi, Lianghui, et al.
Publicado: (2021)

Stat3 Inhibits PTPN13 Expression in Squamous Cell Lung Carcinoma through Recruitment of HDAC5
por: Han, Xiu-juan, et al.
Publicado: (2013)

IL-6/STAT3 Axis Activates Glut5 to Regulate Fructose Metabolism and Tumorigenesis
por: Huang, Xiaoke, et al.
Publicado: (2022)

Inhibition of HDAC6 activity in kidney diseases: a new perspective
por: Ke, Ben, et al.
Publicado: (2018)

A Novel Ferroptosis-Related lncRNAs Signature Predicts Clinical Prognosis and Is Associated With Immune Landscape in Pancreatic Cancer
por: Ping, Haiqin, et al.
Publicado: (2022)

miR-143 promotes angiogenesis and osteoblast differentiation by targeting HDAC7
por: Wang, Renkai, et al.
Publicado: (2020)

Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias
por: Schneckenleithner, Christine, et al.
Publicado: (2011)

STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis
por: D'Amico, Stephen, et al.
Publicado: (2018)

GINS2 Promotes Osteosarcoma Tumorigenesis via STAT3/MYC Axis
por: Ren, Bingkai, et al.
Publicado: (2023)

ATF4-mediated histone deacetylase HDAC1 promotes the progression of acute pancreatitis
por: Deng, Xiaofeng, et al.
Publicado: (2021)

Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling
por: Ye, Xiaohong, et al.
Publicado: (2019)

The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation
por: Zhong, Yu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i2uuehaijnjfvo48ur693cm7bd