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Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

BACKGROUND: Monoallelic expression of autosomal genes has been implicated in human psychiatric disorders. However, there is a paucity of allelic expression studies in human brain cells at the single cell and genome wide levels. RESULTS: In this report, we reanalyzed a previously published single-cel...

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Detalles Bibliográficos
Autores principales: Zhao, Dejian, Lin, Mingyan, Pedrosa, Erika, Lachman, Herbert M., Zheng, Deyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681780/
https://www.ncbi.nlm.nih.gov/pubmed/29126398
http://dx.doi.org/10.1186/s12864-017-4261-x