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Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

BACKGROUND: Epigenetic mechanisms can integrate gene-environment interactions that mediate disease transition from preclinical to clinically overt rheumatoid arthritis (RA). To better understand their role, we evaluated microRNA (miRNA, miR) expression profile in indigenous North American patients w...

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Detalles Bibliográficos
Autores principales: Anaparti, Vidyanand, Smolik, Irene, Meng, Xiaobo, Spicer, Victor, Mookherjee, Neeloffer, El-Gabalawy, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681796/
https://www.ncbi.nlm.nih.gov/pubmed/29126434
http://dx.doi.org/10.1186/s13075-017-1459-x