HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications

Epigenetic signaling pathways are implicated in tumorigenesis and therefore histone deacetylases (HDACs) represent novel therapeutic targets for cancers including multiple myeloma (MM). Although non-selective HDAC inhibitors show anti-MM activities, unfavorable side effects limit their clinical effi...

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Detalles Bibliográficos
Autores principales: Harada, Takeshi, Ohguchi, Hiroto, Grondin, Yohann, Kikuchi, Shohei, Sagawa, Morihiko, Tai, Yu-Tzu, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681897/
https://www.ncbi.nlm.nih.gov/pubmed/28490812
http://dx.doi.org/10.1038/leu.2017.144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681897/
https://www.ncbi.nlm.nih.gov/pubmed/28490812
http://dx.doi.org/10.1038/leu.2017.144

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