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Chronic Inflammation Increases the Sensitivity of Mouse Treg for TNFR2 Costimulation

TNF receptor type 2 (TNFR2) has gained attention as a costimulatory receptor for T cells and as critical factor for the development of regulatory T cells (Treg) and myeloid suppressor cells. Using the TNFR2-specific agonist TNCscTNF80, direct effects of TNFR2 activation on myeloid cells and T cells...

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Detalles Bibliográficos
Autores principales: Schmid, Tobias, Falter, Lena, Weber, Sabine, Müller, Nils, Molitor, Konstantin, Zeller, David, Weber-Steffens, Dorothea, Hehlgans, Thomas, Wajant, Harald, Mostböck, Sven, Männel, Daniela N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681910/
https://www.ncbi.nlm.nih.gov/pubmed/29163535
http://dx.doi.org/10.3389/fimmu.2017.01471