A Novel Missense Mutation of the NSD1 Gene Associated with Overgrowth in Three Generations of an Italian Family: Case Report, Differential Diagnosis, and Review of Mutations of NSD1 Gene in Familial Sotos Syndrome

Sotos syndrome (SoS) is characterized by overgrowth of prenatal onset, learning disability, and characteristic facial appearance; it is usually due to haploinsufficiency of NSD1 gene at chromosome 5q35. An Italian child was born at 37 weeks of gestation (weight 2,910 g, 25th–50th centiles; length 50...

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Detalles Bibliográficos
Autores principales: Laccetta, Gianluigi, Moscuzza, Francesca, Michelucci, Angela, Guzzetta, Andrea, Lunardi, Sara, Lorenzoni, Francesca, Ghirri, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681921/
https://www.ncbi.nlm.nih.gov/pubmed/29164086
http://dx.doi.org/10.3389/fped.2017.00236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681921/
https://www.ncbi.nlm.nih.gov/pubmed/29164086
http://dx.doi.org/10.3389/fped.2017.00236

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