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Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles

INTRODUCTION: Bacterial outer membrane vesicles (OMVs) are naturally produced by all Gram-negative bacteria and, thanks to their plasticity and unique adjuvanticity, are emerging as an attractive vaccine platform. To test the applicability of OMVs in cancer immunotherapy, we decorated them with eith...

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Detalles Bibliográficos
Autores principales: Grandi, Alberto, Tomasi, Michele, Zanella, Ilaria, Ganfini, Luisa, Caproni, Elena, Fantappiè, Laura, Irene, Carmela, Frattini, Luca, Isaac, Samine J., König, Enrico, Zerbini, Francesca, Tavarini, Simona, Sammicheli, Chiara, Giusti, Fabiola, Ferlenghi, Ilaria, Parri, Matteo, Grandi, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681935/
https://www.ncbi.nlm.nih.gov/pubmed/29164053
http://dx.doi.org/10.3389/fonc.2017.00253