Combination Therapy in Fragile X Syndrome; Possibilities and Pitfalls Illustrated by Targeting the mGluR5 and GABA Pathway Simultaneously

Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism. The disorder is characterized by altered synaptic plasticity in the brain. Synaptic plasticity is tightly regulated by a complex balance of different synaptic pathways. In FXS, various synaptic pathw...

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Detalles Bibliográficos
Autores principales: Zeidler, Shimriet, de Boer, Helen, Hukema, Renate K., Willemsen, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681991/
https://www.ncbi.nlm.nih.gov/pubmed/29163043
http://dx.doi.org/10.3389/fnmol.2017.00368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681991/
https://www.ncbi.nlm.nih.gov/pubmed/29163043
http://dx.doi.org/10.3389/fnmol.2017.00368

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