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Restoring Natural Killer Cell Immunity against Multiple Myeloma in the Era of New Drugs

Transformed plasma cells in multiple myeloma (MM) are susceptible to natural killer (NK) cell-mediated killing via engagement of tumor ligands for NK activating receptors or “missing-self” recognition. Similar to other cancers, MM targets may elude NK cell immunosurveillance by reprogramming tumor m...

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Detalles Bibliográficos
Autores principales: Pittari, Gianfranco, Vago, Luca, Festuccia, Moreno, Bonini, Chiara, Mudawi, Deena, Giaccone, Luisa, Bruno, Benedetto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682004/
https://www.ncbi.nlm.nih.gov/pubmed/29163516
http://dx.doi.org/10.3389/fimmu.2017.01444