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Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport

Connexin 43 (Cx43, encoded by GJA1) is a cell-cell communication gap junction protein expressed in all organ systems. It was recently found that GJA1 mRNA undergoes alternative translation to generate N-terminal truncated isoforms, of which GJA1-20k is the most abundant. Here we report a surprising...

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Detalles Bibliográficos
Autores principales: Fu, Ying, Zhang, Shan-Shan, Xiao, Shaohua, Basheer, Wassim A., Baum, Rachel, Epifantseva, Irina, Hong, TingTing, Shaw, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682029/
https://www.ncbi.nlm.nih.gov/pubmed/29163229
http://dx.doi.org/10.3389/fphys.2017.00905