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Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway

Resveratrol (RSV) is used as a protective therapy against diabetic retinopathy. However, the mechanism(s) underlying this protective effect has not been fully elucidated. Bovine retinal capillary endothelial cells (BRECs), an in vitro model, were used to investigate the mechanism of RSV. Our results...

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Detalles Bibliográficos
Autores principales: Li, Jun, Yu, Songping, Ying, Jia, Shi, Tianyan, Wang, Peipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682085/
https://www.ncbi.nlm.nih.gov/pubmed/29213353
http://dx.doi.org/10.1155/2017/7584691