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Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

Degradation of most integral membrane proteins is directed by the endosomal sorting complex required for transport (ESCRT) machinery, which selectively targets ubiquitin-modified cargoes into intralumenal vesicles (ILVs) within multivesicular endosomes (MVEs). To better understand the mechanisms und...

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Detalles Bibliográficos
Autores principales: Frankel, E. B., Shankar, Raakhee, Moresco, James J., Yates, John R., Volkmann, Niels, Audhya, Anjon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682282/
https://www.ncbi.nlm.nih.gov/pubmed/29129923
http://dx.doi.org/10.1038/s41467-017-01636-8