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Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos
Degradation of most integral membrane proteins is directed by the endosomal sorting complex required for transport (ESCRT) machinery, which selectively targets ubiquitin-modified cargoes into intralumenal vesicles (ILVs) within multivesicular endosomes (MVEs). To better understand the mechanisms und...
Autores principales: | Frankel, E. B., Shankar, Raakhee, Moresco, James J., Yates, John R., Volkmann, Niels, Audhya, Anjon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682282/ https://www.ncbi.nlm.nih.gov/pubmed/29129923 http://dx.doi.org/10.1038/s41467-017-01636-8 |
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