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A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells

While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regulation, including translation and turnover. Here we...

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Detalles Bibliográficos
Autores principales: Ju Lee, Hyun, Bartsch, Deniz, Xiao, Cally, Guerrero, Santiago, Ahuja, Gaurav, Schindler, Christina, Moresco, James J., Yates, John R., Gebauer, Fátima, Bazzi, Hisham, Dieterich, Christoph, Kurian, Leo, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682285/
https://www.ncbi.nlm.nih.gov/pubmed/29129916
http://dx.doi.org/10.1038/s41467-017-01744-5