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Thermostable exoshells fold and stabilize recombinant proteins

The expression and stabilization of recombinant proteins is fundamental to basic and applied biology. Here we have engineered a thermostable protein nanoparticle (tES) to improve both expression and stabilization of recombinant proteins using this technology. tES provides steric accommodation and ch...

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Detalles Bibliográficos
Autores principales: Deshpande, Siddharth, Masurkar, Nihar D., Girish, Vallerinteavide Mavelli, Desai, Malan, Chakraborty, Goutam, Chan, Juliana M., Drum, Chester L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682286/
https://www.ncbi.nlm.nih.gov/pubmed/29129910
http://dx.doi.org/10.1038/s41467-017-01585-2