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Fate of methylated/unmethylated H19 imprinting control region after paternal and maternal pronuclear injection

The paternal-allele-specific methylation of the Igf2/H19 imprinting control region (ICR) is established during gametogenesis and maintained throughout development. To elucidate the requirement of the germline passage in the maintenance of the imprinting methylation, we established a system introduci...

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Detalles Bibliográficos
Autores principales: Oji, Asami, Amano, Tomojiro, Maeta, Yasuaki, Hori, Naohiro, Hatsuzawa, Kiyotaka, Sato, Kenzo, Nakanishi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682349/
https://www.ncbi.nlm.nih.gov/pubmed/28674270
http://dx.doi.org/10.1538/expanim.17-0031