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Fate of methylated/unmethylated H19 imprinting control region after paternal and maternal pronuclear injection
The paternal-allele-specific methylation of the Igf2/H19 imprinting control region (ICR) is established during gametogenesis and maintained throughout development. To elucidate the requirement of the germline passage in the maintenance of the imprinting methylation, we established a system introduci...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682349/ https://www.ncbi.nlm.nih.gov/pubmed/28674270 http://dx.doi.org/10.1538/expanim.17-0031 |