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A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway

A high sucrose and high fat (HSHF) diet induces insulin resistance (IR) and increased susceptibility to type 2 diabetes mellitus (T2DM), but the underlying mechanisms are poorly characterized. This study aimed to investigate the molecular mechanisms by which the HSHF diet impairs insulin sensitivity...

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Detalles Bibliográficos
Autores principales: Liu, Yaqian, Yuan, Jifang, Xiang, Lei, Zhao, Yuqiong, Niu, Miaomiao, Dai, Xin, Chen, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682351/
https://www.ncbi.nlm.nih.gov/pubmed/28674285
http://dx.doi.org/10.1538/expanim.17-0010