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Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice

Multiple lines of evidence implicate brain serotonin (5-hydroxytryptamine; 5-HT) system dysfunction in the pathophysiology of stressor-related and anxiety disorders. Here we investigate the influence of constitutively deficient 5-HT synthesis on stressor-related anxiety-like behaviors using Tryptoph...

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Detalles Bibliográficos
Autores principales: Waider, J, Popp, S, Lange, M D, Kern, R, Kolter, J F, Kobler, J, Donner, N C, Lowe, K R, Malzbender, J H, Brazell, C J, Arnold, M R, Aboagye, B, Schmitt-Böhrer, A, Lowry, C A, Pape, H C, Lesch, K P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682603/
https://www.ncbi.nlm.nih.gov/pubmed/28972592
http://dx.doi.org/10.1038/tp.2017.209