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Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections
BACKGROUND: Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum infections. New amplicon sequencing and data analysis protocols are needed for genotyping in epidemiological studies and drug efficac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682641/ https://www.ncbi.nlm.nih.gov/pubmed/29132317 http://dx.doi.org/10.1186/s12864-017-4260-y |