Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

Autophagy has an important renoprotective function and we recently found that autophagy inhibition is involved in cadmium (Cd)-induced nephrotoxicity. Here, we aimed to investigate the protective effect of trehalose (Tre), a novel autophagy activator, against Cd-induced cytotoxicity in primary rat p...

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Detalles Bibliográficos
Autores principales: Wang, Xin-Yu, Yang, Heng, Wang, Min-Ge, Yang, Du-Bao, Wang, Zhen-Yong, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682644/
https://www.ncbi.nlm.nih.gov/pubmed/29022917
http://dx.doi.org/10.1038/cddis.2017.475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682644/
https://www.ncbi.nlm.nih.gov/pubmed/29022917
http://dx.doi.org/10.1038/cddis.2017.475

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