Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis

Pus10 is a pseudouridine synthase present in Archaea and Eukarya, but not in Bacteria and yeast. It has been suggested that the human PUS10 (DOBI) gene is needed during TRAIL-induced apoptosis. We analyzed the role of PUS10 in TRAIL-induced apoptosis by immunofluorescence, immunoblotting and several...

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Detalles Bibliográficos
Autores principales: Jana, Sujata, Hsieh, Andrew C, Gupta, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682645/
https://www.ncbi.nlm.nih.gov/pubmed/28981101
http://dx.doi.org/10.1038/cddis.2017.476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682645/
https://www.ncbi.nlm.nih.gov/pubmed/28981101
http://dx.doi.org/10.1038/cddis.2017.476

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