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STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma

STAT1, which carries tumor suppressor functions in several models, consists of two isoforms, namely STAT1α and STAT1β. The biological function and significance of STAT1β has never been examined in human cancer. We examined STAT1β function in esophageal squamous cell carcinoma (ESCC) by transfecting...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Chen, Yelong, Yun, Hailong, Liu, Zhaoyong, Su, Min, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682650/
https://www.ncbi.nlm.nih.gov/pubmed/28981100
http://dx.doi.org/10.1038/cddis.2017.481