Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis

Receptor-interacting kinase-3 (RIP3) is a key regulator of necroptosis. It has been shown that the expression of RIP3 is silenced in most cancer cells and tissues due to genomic methylation. However, the regulatory mechanisms controlling RIP3 expression in cancer cells have not been fully elucidated...

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Detalles Bibliográficos
Autores principales: Yang, Chengkui, Li, Jun, Yu, Lu, Zhang, Zili, Xu, Feng, Jiang, Lang, Zhou, Xiuxia, He, Sudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682651/
https://www.ncbi.nlm.nih.gov/pubmed/28981102
http://dx.doi.org/10.1038/cddis.2017.483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682651/
https://www.ncbi.nlm.nih.gov/pubmed/28981102
http://dx.doi.org/10.1038/cddis.2017.483

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