Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells

Betulinic acid (BA) exhibits cytotoxic activity against some cancer cells. However, the molecular mechanism of BA against CRC cells was little reported. Here, we proved that BA elicited CRC cells' growth inhibition and apoptosis in a dose-dependent manner. In addition, BA treatment induced auto...

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Detalles Bibliográficos
Autores principales: Wang, Sen, Wang, Kexin, Zhang, Chundong, Zhang, Wanfeng, Xu, Qian, Wang, Yitao, Zhang, Yulin, Li, Yi, Zhang, Ying, Zhu, Huifang, Song, Fangzhou, Lei, Yunlong, Bu, Youquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682653/
https://www.ncbi.nlm.nih.gov/pubmed/28981110
http://dx.doi.org/10.1038/cddis.2017.485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682653/
https://www.ncbi.nlm.nih.gov/pubmed/28981110
http://dx.doi.org/10.1038/cddis.2017.485

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