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Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity

Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by excessive beta amyloid (Aβ) deposition in brain, leading to blood–brain barrier (BBB) disruption. The mechanisms of BBB disruption in AD are still unclear, despite considerable research. The adipokine adiponectin...

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Detalles Bibliográficos
Autores principales: Song, Juhyun, Choi, Seong-Min, Whitcomb, Daniel J, Kim, Byeong C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682657/
https://www.ncbi.nlm.nih.gov/pubmed/29022894
http://dx.doi.org/10.1038/cddis.2017.491