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p53 dynamics orchestrates with binding affinity to target genes for cell fate decision

Emerging evidence support that temporal dynamics is pivotal for signaling molecules in orchestrating smart responses to diverse stimuli. p53 is such a signaling molecule that employs temporal dynamics for the selective activation of downstream target genes and ultimately for cell fate decision. Yet...

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Detalles Bibliográficos
Autores principales: Wu, Mengqiu, Ye, Hui, Tang, Zhiyuan, Shao, Chang, Lu, Gaoyuan, Chen, Baoqiang, Yang, Yuyu, Wang, Guangji, Hao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682658/
https://www.ncbi.nlm.nih.gov/pubmed/29048401
http://dx.doi.org/10.1038/cddis.2017.492