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Alternative mechanisms of miR-34a regulation in cancer

MicroRNA miR-34a is recognized as a master regulator of tumor suppression. The strategy of miR-34a replacement has been investigated in clinical trials as the first attempt of miRNA application in cancer treatment. However, emerging outcomes promote the re-evaluation of existing knowledge and urge t...

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Detalles Bibliográficos
Autores principales: Slabáková, Eva, Culig, Zoran, Remšík, Ján, Souček, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682661/
https://www.ncbi.nlm.nih.gov/pubmed/29022903
http://dx.doi.org/10.1038/cddis.2017.495