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Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve

Type 2 cannabinoid receptor (CB(2)R) has been proposed to promote in vitro meiotic entry of postnatal male germ cells and to maintain the temporal progression of spermatogenesis in vivo. However, no information is presently available on the role played by CB(2)R in male and female fetal gonads. Here...

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Detalles Bibliográficos
Autores principales: De Domenico, Emanuela, Todaro, Federica, Rossi, Gabriele, Dolci, Susanna, Geremia, Raffaele, Rossi, Pellegrino, Grimaldi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682662/
https://www.ncbi.nlm.nih.gov/pubmed/28981118
http://dx.doi.org/10.1038/cddis.2017.496