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Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction

MicroRNAs (miRNAs) play crucial roles in the establishment of pluripotent state by controlling pluripotent network. However, the molecular mechanisms controlling miRNAs during somatic cell reprogramming remain obscure. In this study, we show Gadd45a (growth arrest and DNA-damage-inducible protein 45...

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Detalles Bibliográficos
Autores principales: Li, Linpeng, Chen, Keshi, Wu, Yi, Long, Qi, Zhao, Danyun, Ma, Bochao, Pei, Duanqing, Liu, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682663/
https://www.ncbi.nlm.nih.gov/pubmed/29022923
http://dx.doi.org/10.1038/cddis.2017.497