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MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

Despite DNA methylation occurred in acute kidney injury (AKI), how it influenced progression of AKI remains unclear. Methyl-CpG-binding domain protein 2 (MBD2), a protein readers of methylation, was used to analyze the impact of DNA methylation on vancomycin (VAN)-induced AKI. Here, in cultured huma...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Li, Huiling, Qiu, Shuangfa, Dong, Zheng, Xiang, Xudong, Zhang, Dongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682674/
https://www.ncbi.nlm.nih.gov/pubmed/29022913
http://dx.doi.org/10.1038/cddis.2017.509